New Information on Vanilla's Medicinal Properties

Site visitor Bill Oliver sent some remarkable and very interesting information regarding vanilla's ability to repair DNA strands and its anti-mutagenic properties.http://ehp.niehs.nih.gov/members/1997/Suppl-4/stoner-full.html

This is the key paragraph in the monograph:

--Inducers of DNA Repair. There are three possible chemopreventive mechanisms that involve DNA repair (70,71). The first is an increase in the overall level of DNA repair. An example of a naturally occurring chemical that increases the level of DNA repair is vanillin, which inhibits mammalian cell mutagenicity (72). The mechanisms through which vanillin promotes DNA repair have not been determined. Second, the enzyme poly(ADP-ribosyl)transferase (ADPRT) is involved in modulation of DNA damage (73,74), and the level of this enzyme is reduced by chemical carcinogens (75). N-Acetylcysteine prevents the decrease in ADPRT caused by the carcinogen 2-acetylaminofluorene (AAF) (75). The third mechanism is suppression of error-prone DNA repair. Protease inhibitors depress error-prone repair in bacteria (76), and it has been suggested that they could prevent carcinogenesis by inhibiting an error-prone repair system activated by proteases that, in turn, are induced by tumor promoters (!
77).--

Citations of additional information about vanilla as medicine:

http://nar.oupjournals.org/cgi/content/full/31/19/5501

or

http://www3.interscience.wiley.com/cgi-bin/abstract/109741309/ABSTRACT

or (scroll down the page to his information):

http://www.umdnj.edu/umcweb/marketing_and_communications/publications/umdnj_magazine/spring2004/6.htm Here there are two paragraphs about the work of Jeffrey D. Laskin, PhD on the prevention of prostrate cancer.

I intend to follow up on this with more information as I can find it. I would like to find out more about doseage for possible cancer prevention as well as doseage as an integrative therapy treatment for cancer. In the meantime, if any readers have additional information, please either post here or contact me at rain@vanilla.com